Pet supplements / best for calming

Best calming supplements, ranked.

L-theanine, alpha-casozepine, L-tryptophan, and calming blends for stress and anxiety.

Ranked by PetScored composite (evidence quality 30%, active dose 25%, ingredient clarity 15%, safety and manufacturing 15%, value 15%). This ranking is our opinion under a published rubric, not veterinary advice. A product can rank below a peer because its headline active is weakly evidenced or its dose is hidden, even when it is well made.

  1. Pet Naturals Calming for Dogs and Cats

    The studied L-theanine form, fully disclosed and very cheap per day, but at 5 mg it is well under the studied dose; weak evidence and a low dose hold it to Mixed.

    Dogs & catssoft chew
    7.3Mixed
  2. VetriScience Composure Calming Chews

    A calming chew scored on its disclosed L-theanine (the studied Suntheanine form); the C3 colostrum complex is not in our evidence library and at 21 mg the L-theanine is below the studied dose, so it lands Mixed.

    Dogs & catssoft chew
    7.3Mixed
  3. Purina Pro Plan Veterinary Supplements Calming Care Probiotic

    The one calming product with a dedicated canine anxiety RCT (B. longum BL999), at the studied dose and fully disclosed; no NASC seal and a high cost per day hold it to Mixed.

    Dogspowder
    6.9Mixed
  4. NaturVet Quiet Moments Calming Aid Soft Chews

    Transparent and inexpensive, but a weakly-evidenced calming active (L-tryptophan) delivered well below the studied dose for a 22 lb dog keeps it Mixed.

    Dogssoft chew
    6.8Mixed

Affiliate links on individual scorecards never affect the score. See the supplement methodology, affiliate disclosure, and medical disclaimer.